Prostaglandin E1 Is an Efficient Molecular Tool for Forest Leech Blood Sucking

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Tridegin, a new peptidic inhibitor of factor XIIIa, from the blood-sucking leech Haementeria ghilianii.

1. Crude salivary gland extract of the giant Amazon leech, Haementeria ghilianii, contains an inhibitor of plasma factor XIIIa. 2. The inhibitory agent was purified to homogeneity by anion-exchange, cation-exchange, gel-filtration and reverse-phase chromatography to yield a single band on SDS/PAGE with an apparent molecular mass of 7.3 kDa. It has been named tridegin. 3. Micro-sequencing of pro...

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ژورنال

عنوان ژورنال: Frontiers in Veterinary Science

سال: 2021

ISSN: 2297-1769

DOI: 10.3389/fvets.2020.615915